Omar M Khan Selected Research

geranylgeranyltransferase type-I (protein geranylgeranyltransferase)

1/2019	Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions.
2/2013	Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice.
2/2011	Geranylgeranyltransferase type I (GGTase-I) deficiency hyperactivates macrophages and induces erosive arthritis in mice.

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Omar M Khan Research Topics

Disease

3	Rheumatoid Arthritis 01/2019 - 02/2011
3	Inflammation (Inflammations) 01/2019 - 02/2011
2	Neoplasms (Cancer) 01/2021 - 01/2018
2	Arthritis (Polyarthritis) 01/2019 - 02/2011
2	Atherosclerosis 10/2014 - 02/2013
1	Myeloid Leukemia (Leukemia, Myelocytic) 01/2021
1	Colonic Neoplasms (Colon Cancer) 01/2018
1	Colorectal Neoplasms (Colorectal Cancer) 01/2018
1	Pain (Aches) 01/2017
1	Chronic Pain 01/2017
1	Stroke (Strokes) 01/2009

Drug/Important Bio-Agent (IBA)

5	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2011
3	geranylgeranyltransferase type-I (protein geranylgeranyltransferase)IBA 01/2019 - 02/2011
2	CytokinesIBA 01/2019 - 02/2013
1	TubulinIBA 01/2021
1	Guanosine Triphosphate (GTP)IBA 01/2019
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2019
1	Messenger RNA (mRNA)IBA 01/2018
1	Oncogene Proteins (Oncogene Protein)IBA 01/2018
1	Deubiquitinating EnzymesIBA 01/2018
1	Pharmaceutical PreparationsIBA 01/2017
1	Opioid Analgesics (Opioids)IBA 01/2017
1	Apolipoproteins E (ApoE)IBA 10/2014
1	CholesterolIBA 02/2013
1	LDL Receptors (LDL Receptor)IBA 02/2013
1	Blood Glucose (Blood Sugar)IBA 01/2009

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 01/2021
1	Pain Management 01/2017
1	Therapeutics 01/2017